NHLBI Growth and Health Study (NGHS) - Catalog

Name

NHLBI Growth and Health Study (NGHS)

Accession Number

HLB00270310a

Acronym

NGHS

Related studies

BSI Study IDs

NGH

Is public use dataset

False

Keywords

Has Study Datasets

True

Has Specimens

True

Specimen ID Type

Coded

Study Website

The Framingham Heart Study Group requires that the requestor must obtain full or expedited IRB/Ethics Committee review and approval to obtain these data. Waivers or a determination that the research is exempt from ethical regulations do not suffice.

False

Clinical Trial URLs
https://clinicaltrials.gov/ct2/show/NCT00005132
Study type

Epidemiology Study

Collection Type

Open BioLINCC Study

Cohort type

Pediatric

Interventions

Study Open Date (Data)

2009-10-01

Study Open Date (Specimens)

2010-05-14

Date materials available

2008-10-13

Last updated

2006-01-27

Study period

1985-2000

Study Contacts
NHLBI Division

DCVS

Classification

Heart

HIV study classification

non-HIV

COVID study classification

non-COVID

Pre-Website # of Specimens Shipped

217

# of Returned Specimens

0

Primary Publication URLs
N/A
Conditions

Cardiovascular Diseases
Coronary Disease
Heart Diseases
Hypertension
Obesity

Objectives

To investigate racial differences in dietary, physical activity, family, and psychosocial factors associated with the development of obesity from pre-adolescence through maturation between African-American and white girls. Secondarily, the NGHS sought to examine the effects of obesity on cardiovascular disease risk factors.

Background

Obesity is a major contributing factor to several predictors of coronary heart disease such as hypertension, a poor lipid profile and diabetes. Both genetic and environmental factors play a significant role in the development of obesity, and there is evidence to suggest that obesity in childhood will likely carry over into adulthood. Prevention of obesity in early childhood could provide significant long term health benefits. A greater understanding of the factors contributing to childhood obesity is required for the establishment of effective weight reduction intervention programs. To this end, the National Growth and Health Study was initiated in 1985 as a multicenter study of the development of obesity among black and white pre-adolescent girls.

Participants

The NHLBI National Growth and Health Study recruited girls 9 and 10 years of age in two communities (Richmond, California and Cincinnati, Ohio) and also from families enrolled in a health maintenance organization in the Washington, D.C. area. A total of 2,379 girls were enrolled in the study between 1987-88 and were followed for 9 years. Slightly more than half of the cohort was African-American.

Design

Subjects had annual examinations, and data collected included: physical examination, anthropometric measurements, dietary information including food pattern and nutrient intake, physical activity, lipid, lipoprotein, and apolipoprotein profiles, family socioeconomic status, and psychosocial information.

Conclusions

Disease classification

Publications

Mat types

Serum

The study population available in BioLINCC study data may be lower than total study enrollment due to Informed Consent restrictions and other factors.

  • Subjects

    2,379


    Last Modified: April 16, 2024, 3:06 p.m.
  • Age

     

    Total Subjects

    9

    1,156

    10

    1,222

    Unknown

    1


    Last Modified: April 16, 2024, 3:06 p.m.
  • Sex

    Female


    Last Modified: July 28, 2014, 4:12 p.m.
  • Race

     

    Total Subjects

    White

    1,166

    Black

    1,213


    Last Modified: April 16, 2024, 3:06 p.m.

Please note that biospecimen availability is subject to review by the NHLBI, BioLINCC, and the NHLBI Biorepository. Certain biospecimens may not be made available for your request. Section 3 of the BioLINCC handbook describes the components of the review process

  • Material Types

    Serum


    Last Modified: April 16, 2024, 3:07 p.m.
  • General Freeze/Thaw Status

    Serum - Majority unthawed


    Last Modified: April 16, 2024, 3:07 p.m.
  • Visits (Vials)

    04/16/2024

     

    Serum

    Total Vials

    Unknown

    245

    245

    Baseline

    2,841

    2,841

    Year 3

    4,091

    4,091

    Year 5

    4,114

    4,114

    Year 7

    3,579

    3,579

    Year 10

    4,534

    4,534

     


    Last Modified: April 16, 2024, 3:06 p.m.
  • Visits (Subjects)

    04/16/2024

     

    Serum

    Total number of subjects

    Average volume (mL) per subject

    Unknown

    162

    0.64

    Baseline

    2,542

    0.53

    Year 3

    1,569

    2.51

    Year 5

    1,379

    3.27

    Year 7

    1,280

    3.17

    Year 10

    1,300

    1.50

     


    Last Modified: April 16, 2024, 3:06 p.m.