NHLBI Growth and Health Study (NGHS) - Catalog
NHLBI Growth and Health Study (NGHS)
HLB00270310a
NGHS
NGH
False
True
True
Coded
False
Epidemiology Study
Open BioLINCC Study
Pediatric
2009-10-01
2010-05-14
2008-10-13
2006-01-27
1985-2000
DCVS
Heart
non-HIV
non-COVID
217
0
No
No
No
No
No
No
None.
Cardiovascular Diseases
Coronary Disease
Heart Diseases
Hypertension
Obesity
To investigate racial differences in dietary, physical activity, family, and psychosocial factors associated with the development of obesity from pre-adolescence through maturation between African-American and white girls. Secondarily, the NGHS sought to examine the effects of obesity on cardiovascular disease risk factors.
Obesity is a major contributing factor to several predictors of coronary heart disease such as hypertension, a poor lipid profile and diabetes. Both genetic and environmental factors play a significant role in the development of obesity, and there is evidence to suggest that obesity in childhood will likely carry over into adulthood. Prevention of obesity in early childhood could provide significant long term health benefits. A greater understanding of the factors contributing to childhood obesity is required for the establishment of effective weight reduction intervention programs. To this end, the National Growth and Health Study was initiated in 1985 as a multicenter study of the development of obesity among black and white pre-adolescent girls.
The NHLBI National Growth and Health Study recruited girls 9 and 10 years of age in two communities (Richmond, California and Cincinnati, Ohio) and also from families enrolled in a health maintenance organization in the Washington, D.C. area. A total of 2,379 girls were enrolled in the study between 1987-88 and were followed for 9 years. Slightly more than half of the cohort was African-American.
Subjects had annual examinations, and data collected included: physical examination, anthropometric measurements, dietary information including food pattern and nutrient intake, physical activity, lipid, lipoprotein, and apolipoprotein profiles, family socioeconomic status, and psychosocial information.
Serum
The study population available in BioLINCC study data may be lower than total study enrollment due to Informed Consent restrictions and other factors.
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Subjects
2379
Last Modified: July 28, 2014, 4:12 p.m. -
Age
Frequency
Percent
Unknown
1
0.04
9
1156
48.59
10
1222
51.37
Last Modified: March 7, 2016, 4:46 p.m. -
Sex
Female
Last Modified: July 28, 2014, 4:12 p.m. -
Race
Frequency
Percent
White
1166
49.01
Black
1213
50.99
Last Modified: Aug. 26, 2015, 3:43 p.m.
Please note that biospecimen availability is subject to review by the NHLBI, BioLINCC, and the NHLBI Biorepository. Certain biospecimens may not be made available for your request. Section 3 of the BioLINCC handbook describes the components of the review process
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Material Types
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General Freeze/Thaw Status
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Visits (Vials)
Last Modified: March 8, 2021, 4:28 p.m. -
Visits (Subjects)
Last Modified: March 8, 2021, 4:28 p.m.