NHLBI Growth and Health Study (NGHS) - Catalog

  • Name

    NHLBI Growth and Health Study (NGHS)

  • Accession Number

    HLB00270310a

  • Acronym

    NGHS

  • Related studies
  • BSI Study IDs

    NGH

  • Is public use dataset

    False

  • Keywords
  • Ingestion Status
    Released
  • Has Study Datasets

    True

  • Has Specimens

    True

  • Specimen ID Type
    Coded
  • Study Website
  • The Framingham Heart Study Group requires that the requestor must obtain full or expedited IRB/Ethics Committee review and approval to obtain these data. Waivers or a determination that the research is exempt from ethical regulations do not suffice.

    False

  • Clinical Trial URLs
    NCT00005132
  • Study type
    Epidemiology Study
  • Collection Type
    Open BioLINCC Study
  • Cohort type
    Pediatric
  • Interventions
  • Study Open Date (Data)

    2009-10-01

  • Study Open Date (Specimens)

    2010-05-14

  • Date materials available

    2008-10-13

  • Last updated

    2006-01-27

  • Study period

    1985-2000

  • Study Contacts
  • NHLBI Division

    DCVS

  • Classification
    Heart
  • HIV study classification
    non-HIV
  • COVID study classification
    non-COVID
  • Pre-Website # of Specimens Shipped

    217

  • # of Returned Specimens

    0

  • Primary Publication URLs
    N/A
  • Commercial use data restrictions
    No
  • Data restrictions based on area of research
    No
  • Commercial use specimen restrictions
    No
  • Non-genetic use specimen restrictions based on area of use
    No
  • Genetic use of specimens allowed?
    No
  • Genetic use area of research restrictions
    No
  • Specific Consent Restrictions

    None.

  • Conditions
    Cardiovascular Diseases
    Coronary Disease
    Heart Diseases
    Hypertension
    Obesity
  • Objectives

    To investigate racial differences in dietary, physical activity, family, and psychosocial factors associated with the development of obesity from pre-adolescence through maturation between African-American and white girls. Secondarily, the NGHS sought to examine the effects of obesity on cardiovascular disease risk factors.

  • Background

    Obesity is a major contributing factor to several predictors of coronary heart disease such as hypertension, a poor lipid profile and diabetes. Both genetic and environmental factors play a significant role in the development of obesity, and there is evidence to suggest that obesity in childhood will likely carry over into adulthood. Prevention of obesity in early childhood could provide significant long term health benefits. A greater understanding of the factors contributing to childhood obesity is required for the establishment of effective weight reduction intervention programs. To this end, the National Growth and Health Study was initiated in 1985 as a multicenter study of the development of obesity among black and white pre-adolescent girls.

  • Participants

    The NHLBI National Growth and Health Study recruited girls 9 and 10 years of age in two communities (Richmond, California and Cincinnati, Ohio) and also from families enrolled in a health maintenance organization in the Washington, D.C. area. A total of 2,379 girls were enrolled in the study between 1987-88 and were followed for 9 years. Slightly more than half of the cohort was African-American.

  • Design

    Subjects had annual examinations, and data collected included: physical examination, anthropometric measurements, dietary information including food pattern and nutrient intake, physical activity, lipid, lipoprotein, and apolipoprotein profiles, family socioeconomic status, and psychosocial information.

  • Conclusions
  • Disease classification
  • Publications
  • Mat types
    Serum
  • Network

The study population available in BioLINCC study data may be lower than total study enrollment due to Informed Consent restrictions and other factors.

  • Subjects

    2,379


    Last Modified: April 16, 2024, 3:06 p.m.
  • Age

     

    Total Subjects

    9

    1,156

    10

    1,222

    Unknown

    1


    Last Modified: April 16, 2024, 3:06 p.m.
  • Sex

    Female


    Last Modified: July 28, 2014, 4:12 p.m.
  • Race

     

    Total Subjects

    White

    1,166

    Black

    1,213


    Last Modified: April 16, 2024, 3:06 p.m.

Please note that biospecimen availability is subject to review by the NHLBI, BioLINCC, and the NHLBI Biorepository. Certain biospecimens may not be made available for your request. Section 3.0 of the BioLINCC Handbook describes the components of the review process.

  • Material Types

    Serum


    Last Modified: April 16, 2024, 3:07 p.m.
  • General Freeze/Thaw Status

    Serum - Majority unthawed


    Last Modified: April 16, 2024, 3:07 p.m.
  • Visits (Vials)

    04/16/2024

     

    Serum

    Total Vials

    Unknown

    245

    245

    Baseline

    2,841

    2,841

    Year 3

    4,091

    4,091

    Year 5

    4,114

    4,114

    Year 7

    3,579

    3,579

    Year 10

    4,534

    4,534

     


    Last Modified: April 16, 2024, 3:06 p.m.
  • Visits (Subjects)

    04/16/2024

     

    Serum

    Total number of subjects

    Average volume (mL) per subject

    Unknown

    162

    0.64

    Baseline

    2,542

    0.53

    Year 3

    1,569

    2.51

    Year 5

    1,379

    3.27

    Year 7

    1,280

    3.17

    Year 10

    1,300

    1.50

     


    Last Modified: April 16, 2024, 3:06 p.m.