Asthma Clinical Research Network (ACRN) Measuring Inhaled Corticosteroid Efficacy (MICE)
Note that you will be prompted to log in or register an account
Accession Number
HLB00580606a
Study Type
Clinical Trial
Collection Type
Open BioLINCC Study
See bottom of this webpage for request information
Study Period
1999-2000
NHLBI Division
DLD
Dataset(s) Last Updated
January 3, 2018
Clinical Trial URLs
https://clinicaltrials.gov/ct2/show/NCT00000577
Primary Publication URLs
N/A
Consent
Commercial Use Data Restrictions No
Data Restrictions Based On Area Of Research No
Objectives
The purpose of this study was to compare the relative beneficial and systemic effects in a dose-response relationship for 2 ICSs.
Background
A clinical model is needed to compare inhaled corticosteroids (ICS) with respect to efficacy.
Participants
30 asthmatic individuals 18 to 55 years of age. This was a feasibility study, not a comparative trial, therefore the sample size calculation was based on an appropriate sample size for estimating the common variance with some level of precision.
Conclusions
High-dose ICS therapy did not significantly increase the efficacy of measures that were evaluated but it did increase the systemic effect measure, overnight cortisol secretion.
Please note that researchers must be registered on this site to submit a request, and you will be prompted to log in. If you are not registered on this site, you can do so via the Request button. Registration is quick, easy and free.
Resources Available
Study Datasets OnlyStudy Documents
Persons using assistive technology may not be able to fully access information in the study documents. For assistance, Contact BioLINCC and include the web address and/or publication title in your message. If you need help accessing information in different file formats such as PDF, XLS, DOC, see Instructions for Downloading Viewers and Players.