Retrovirus Epidemiology Donor Study-II (REDS II) Donation and Deferral Database (CORE)

Note that you will be prompted to log in or register an account

Accession Number

Study Type
Epidemiology Study

Collection Type
Open BioLINCC Study See bottom of this webpage for request information

Study Period
2006 - 2009

NHLBI Division

Dataset(s) Last Updated
January 3, 2018

Primary Publication URLs


Commercial Use Data Restrictions No

Data Restrictions Based On Area Of Research No


The objective of the REDS-II Donation and Deferral Database effort was to build a well-developed blood donation database and deferral database to provide insight on critical issues within the blood banking community.


The collection of selected data on donors from all REDS-II blood centers and its compilation into central databases was a major component of the RED-II program. These databases provide a robust research tool to evaluate characteristics associated with blood donation in the U.S. Summarily, the donation and deferral data offer a look at the demographic characteristics of donors including racial/ethnic differences, donation patterns of first-time and repeat donors, and deferral trends. It can also be used to derive prevalence and incidence estimates of infectious disease (e.g. HIV, HBV, HCV), and evaluate the impact of changing donor screening methodology and test performance.

Four calendar years worth of data were collected and compiled that include donation visits made on January 1, 2006 through December 31, 2009. Due to the size of the REDS-II Donation and Deferral database, eight data files have been created in SAS version 9.2, dividing the data by the year of data collected – 2006, 2007, 2008 and 2009.


Six blood centers participated in REDS-II: American Red Cross New England Region, Dedham, MA; the American Red Cross Southern Region, Atlanta, Georgia; the Blood Centers of the Pacific, San Francisco, California; the Blood Center of Wisconsin, Milwaukee, Wisconsin; the Hoxworth Blood Center/University of Cincinnati Medical Center, Cincinnati, Ohio; and the Institute for Transfusion Medicine, Pittsburgh, Pennsylvania. The REDS-II centers represent both geographically and demographically diverse populations. Each year of data contains information from approximately 1.3 million donations from more than 700,000 individual donors.

Data Files

Donation Data Files

These files contain demographic and donation characteristics such as transfusion information, pregnancy history, and infectious disease markers for donation visits. Types of information for each donation visit include the date of donation, previous donation dates, donation location, the type and procedure of the donation, screening results and donor-specific information such as birth date, gender, and race/ethnicity, height, weight, country of birth, and highest level of education.

Deferral Data Files

These files contain data on the demographic and deferral characteristics of deferred donations including transfusion information, pregnancy history, and deferral reasons for deferral visits. Date of visit and the length of the deferral, including the effective and eligibility dates, are also included.

Please note that researchers must be registered on this site to submit a request, and you will be prompted to log in. If you are not registered on this site, you can do so via the Request button. Registration is quick, easy and free.

Resources Available

Study Datasets Only

Study Documents

Persons using assistive technology may not be able to fully access information in the study documents. For assistance, Contact BioLINCC and include the web address and/or publication title in your message. If you need help accessing information in different file formats such as PDF, XLS, DOC, see Instructions for Downloading Viewers and Players.