News
New Study: CCTRN-PACE (data)
Posted on September 17, 2019
A new study, Cardiovascular Cell Therapy Research Network (CCTRN) Clinical and MR Imaging Assessments in Patients With Intermittent Claudication Following Injection of Bone Marrow Derived ALDH Bright Cells (PACE), has been posted to BioLINCC. Data from this study are available for requests.
Funding Opportunities Added
Posted on August 30, 2019
New information regarding secondary data and/or biospecimen analysis funding opportunities from NHLBI, NIDDK, and FDA has been added to the funding opportunities page. These NIH Exploratory (R21) grant funding opportunities may be applicable to research using BioLINCC resources. Additionally included is an NHLBI released Notice of Special Interest (NOSI) on Data Science R01 applications. Please see the funding opportunities page, which includes links to the NIH grant announcements, for more information.
New Study: WRAP-IPF (data)
Posted on August 29, 2019
A new study, Weighing Risks and Benefits of Laparoscopic Anti-Reflux Surgery in Patients With Idiopathic Pulmonary Fibrosis (WRAP-IPF), has been posted to BioLINCC. Data from this study are available for requests.
New Study: CCTRN-FOCUS (data)
Posted on August 26, 2019
A new study, Cardiovascular Cell Therapy Research Network (CCTRN) Randomized, Controlled, Phase II, Double-Blind Trial of Intramyocardial Injection of Autologous Bone Marrow Mononuclear Cells Under Electromechanical Guidance for Patients With Chronic Ischemic Heart Disease and Left Ventricular Dysfunction (FOCUS), has been posted to BioLINCC. Data from this study are available for requests.
New Study: REDS III (data)
Posted on August 23, 2019
A new study, Recipient Epidemiology and Donor Evaluation Study-III (REDS-III) Vein to Vein Databases, has been posted to BioLINCC. Data from this study are available for requests.
New Study: WHI-CTOS (data)
Posted on August 16, 2019
A new study, Women's Health Initiative: Clinical Trial and Observational Study (WHI-CTOS), has been posted to BioLINCC. This study incorporates prior releases of WHI-CT and WHI-OS data into one unified study.
Data from this study are available for requests.
New Study: GUIDE-IT (data)
Posted on July 31, 2019
A new study, Guiding Evidence Based Therapy Using Biomarker Intensified Treatment in Heart Failure (GUIDE-IT), has been posted to BioLINCC. Data from this study are available for requests.
New Study: THAPCA-IH (data)
Posted on July 31, 2019
A new study, Therapeutic Hypothermia After Pediatric Cardiac Arrest (In-Hospital) (THAPCA-IH), has been posted to BioLINCC. Data from this study are available for requests.
New Study: BMT CTN-0301 (data)
Posted on July 8, 2019
A new study, Blood and Marrow Clinical Trials Network (BMT CTN) Fludarabine-based Conditioning for Severe Aplastic Anemia (0301), has been posted to BioLINCC. Data from this study are available for requests.
Data Update for SPIROMICS
Posted on June 28, 2019
Data have been updated for the Subpopulations and Intermediate Markers in COPD Study (SPIROMICS). Now available are data from the SPIROMICS I main study as well as the SPIROMICS Bridge phone call follow-up period (period between SPIROMICS I NIH contract and SPIROMICS II grant).
New Study: SPRINT (data and specimens)
Posted on June 24, 2019
A new study, Systolic Blood Pressure Intervention Trial (SPRINT), has been posted to BioLINCC. Data and specimens from this study are available for requests.
The SPRINT-POP data, based on the primary outcome paper and previously available for request through the BioLINCC website, have been incorporated into this SPRINT full study data release.
Data Update for Intermacs
Posted on May 13, 2019
Data have been updated for Interagency Registry for Mechanically Assisted Circulatory Support (Intermacs) to include data from the Medical Arm of Mechanical Circulatory Support (MedaMACS) Study and additional data from the Intermacs and Pedimacs studies.
New Study: CCTRN-LateTIME (data)
Posted on May 7, 2019
A new study, Cardiovascular Cell Therapy Research Network (CCTRN) A Phase II, Randomized, Controlled, Double-Blind Pilot Trial Evaluating the Safety and Effect of Administration of Bone Marrow Mononuclear Cells Two to Three Weeks Following Acute Myocardial Infarction (LateTIME), has been posted to BioLINCC. Data from this study are available for requests.
New Study: CCTRN-TIME (data)
Posted on May 7, 2019
A new study, Cardiovascular Cell Therapy Research Network (CCTRN) Transplantation in Myocardial Infarction Evaluation (TIME) Protocol: A Phase II, Randomized, Controlled, Double-Blind Trial Evaluating the Effect of Timing on the Administration of Bone Marrow Mononuclear Cells (BMMNCs) Versus Placebo in Patients With Acute Myocardial Infarction, has been posted to BioLINCC. Data from this study are available for requests.
Data Update for ARIC Study
Posted on May 3, 2019
Data have been updated for the Atherosclerosis Risk in Communities Study (ARIC) study to include two additional ancillary studies: adjudicated cancer outcomes (through 2012) and additional biomarkers from stored V2 blood . Now available are data from v1-v5 examination cycles, collated annual follow-up communication data for contact years 2-26, and follow-up for mortality, heart disease, and stroke events through 2014 in addition to 7 ancillary studies.
Data Update for MESA
Posted on April 30, 2019
Data have been updated for the Multi-Ethnic Study of Atherosclerosis (MESA) to include ancillary studies #205 on Brachial IMT and #113 on Exam 5 Sleep. Now available are data through exam 5, follow-up event data through year 10, and data from eight ancillary studies.
New Study: BMT CTN-0902 (data)
Posted on April 4, 2019
A new study, Blood and Marrow Transplant Clinical Trials Network (BMT CTN) A Phase III Randomized, Multicenter Trial Testing Whether Exercise or Stress Management Improves Functional Status and Symptoms of Autologous and Allogeneic Recipients (0902), has been posted to BioLINCC. Data from this study are available for requests.
New Study: CHOICES (data)
Posted on March 26, 2019
A new study, Choosing Healthy Options in College Environments and Settings (CHOICES), has been posted to BioLINCC. Data from this study are available for requests.
Data Update for JHS
Posted on February 27, 2019
Data have been updated for The Jackson Heart Study (JHS). The data now include visit 1-3 examination cycles, collated annual follow-up communication data through 2016, and follow-up for mortality, heart disease, and stroke events through 2014.
Data Update for FHS-Gen III
Posted on February 5, 2019
Data have been updated for the Framingham Heart Study (FHS) Third Generation (Gen III), OMNI 2, and New Offspring (NOS) Cohorts. The data now include examination data from the first 2 clinical exams, selected ancillary data and event follow-up through 2014. Also included are the OMNI 2 and NOS cohorts.
Data Update for FHS-Cohort
Posted on January 28, 2019
Data have been updated for the Framingham Heart Study-Cohort (FHS-Cohort). The data now include examination data from the first 32 clinical exams, selected ancillary data, and event follow-up through 2014.
Data Update for OMNI Heart
Posted on January 24, 2019
Data have been updated for the Optimal Macronutrient Intake Trial to Prevent Heart Disease (OMNI Heart) study. The data now include forms data from the medication, patient history, physical activity, participant-reported symptoms, and diet acceptability questionnaires.
New Study: BMT CTN-0803 (data)
Posted on January 15, 2019
A new study, Blood and Marrow Transplant Clinical Trials Network (BMT CTN) High Dose Chemotherapy With Autologous Stem Cell Rescue for Aggressive B Cell Lymphoma and Hodgkin Lymphoma in HIV-infected Patients (0803), has been posted to BioLINCC. Data from this study are available for requests.
Data Update for FHS-Offspring
Posted on January 4, 2019
Data have been updated for the Framingham Heart Study-Offspring (FHS-OS). The data now include data from the first 9 clinical exams, selected ancillary data, and event follow-up through 2014. Also included are the first 4 exams from the OMNI 1 cohort.
Note that phenotypic data in the NHLBI data repository now mirror the phenotypic data in dbGaP.
New Study: ACS-QUIK (data)
Posted on December 6, 2018
A new study, Acute Coronary Syndrome Quality Improvement in Kerala (ACS-QUIK) Cluster Randomized, Stepped Wedge Multi-center Implementation of a Locally-Developed Quality Improvement Toolkit, has been posted to BioLINCC. Data from this study are available for requests.
New Study: CARE-TREXA (data)
Posted on November 27, 2018
A new study, Childhood Asthma Research and Education (CARE) Network Trial - Treating children to Prevent Exacerbations of Asthma (TREXA), has been posted to BioLINCC. Data from this study are available for requests.
Data Update for HCHS-SOL
Posted on November 9, 2018
Data have been updated for the Hispanic Community Health Study / Study of Latinos (HCHS-SOL). The data now include data from the Youth ancillary study.
New Study: BMT CTN-0403 (data)
Posted on November 8, 2018
A new study, Blood and Marrow Transplant Clinical Trials Network (BMT CTN) A Randomized Double-Blind, Placebo-Controlled Trial of Soluble Tumor Necrosis Factor Receptor: Enbrel (Etanercept) for the Treatment of Acute Non-Infectious Pulmonary Dysfunction (Idiopathic Pneumonia Syndrome) Following Allogeneic Cell Transplantation (0403), has been posted to BioLINCC. Data from this study are available for requests.
New Study: BMT CTN-0802 (data)
Posted on October 31, 2018
A new study, Blood and Marrow Clinical Trials Network (BMT CTN) A Multi-Center, Randomized, Double Blind, Phase III Trial Evaluating Corticosteroids with Mycophenolate Mofetil vs. Corticosteroids with Placebo as Initial Systemic Treatment of Acute GVHD (0802), has been posted to BioLINCC. Data from this study are available for requests.
New Study: HCS (data)
Posted on October 31, 2018
A new study, Healthy Communities Study (HCS), has been posted to BioLINCC. Data from this study are available for requests.
Data Update for ARIC Study
Posted on September 19, 2018
Data have been updated for the Atherosclerosis Risk in Communities Study (ARIC). Now included are v1-v5 examination cycles, collated annual follow-up communication data for contact years 2-26, and follow-up for mortality, heart disease, and stroke events through 2014.
There are three longitudinal datasets available in this release. The longitudinal datasets cover data collected across multiple exams in three specific domains: analytes, spirometry, cognitive function.
Notice of Addition of AIDS Application Due Dates for RFA-HL-17-022
Posted on December 5, 2017
AIDS application due dates have been added to the Funding Opportunity Announcement for RFA-HL-17-022 "Maximizing the Scientific Value of the NHLBI Biorepository: Scientific Opportunities for Exploratory Research (R21)". The next application due date is January 7, 2020.
For more information, please visit: https://grants.nih.gov/grants/guide/notice-files/NOT-HL-17-565.html
Novel Evaluation of GenTAC Images is Available
Posted on November 2, 2017
The Imaging Core Lab of the National Registry of Genetically Triggered Thoracic Aortic Aneurysms (GenTAC) is now considering applications from researchers who have obtained GenTAC data through BioLINCC and who wish to have additional or novel evaluation of GenTAC images beyond the image readings obtained under the original GenTAC study protocol. The application form, instructions, and contact information for the Imaging Core Lab will be made available for request upon approval and fulfillment of a GenTAC data request through BioLINCC.
New BioLINCC Manuscript
Posted on June 15, 2017
A new open-access paper about BioLINCC metrics and results is now available on PLOS ONE:
Giffen CA, Wagner EL, Adams JT, Hitchcock DM, Welniak LA, Brennan SP, Carroll LE. “Providing researchers with online access to NHLBI biospecimen collections: The results of the first six years of the NHLBI BioLINCC program”.
Funding Opportunity: NHLBI R21 PAR-17-004
Posted on February 16, 2017
This funding opportunity is to stimulate the use of existing human datasets for well-focused secondary analyses to investigate novel scientific ideas or new models, systems, tools, methods, or technologies that have the potential for significant impact on biomedical or biobehavioral research in areas relevant to the NHLBI mission. The next application due date is February 22, 2019.
For more information on PAR-17-004 please visit:
https://grants.nih.gov/grants/guide/pa-files/PAR-17-004.html
Funding Opportunity: NHLBI R21 RFA-HL-17-022
Posted on February 16, 2017
This funding opportunity is to support meritorious exploratory research relevant to the NHLBI mission using the biospecimen collections that are stored in the NHLBI Biorepository and that are available through BioLINCC. The next application due date is October 17, 2019.
For more information on RFA-HL-17-022 please visit:
https://grants.nih.gov/grants/guide/rfa-files/RFA-HL-17-022.html
and
https://grants.nih.gov/grants/guide/notice-files/NOT-HL-17-494.html
FAQ for RFA-HL-17-022 now available
Posted on November 14, 2016
The RFA-HL-17-022 funding opportunity now has a FAQ available here: https://www.nhlbi.nih.gov/grants-and-training/funding-opportunities-and-contacts/all-funding-opportunity-announcements-1745