Biologic Specimen and Data Repository Information Coordinating Center

News

PETAL-BLUE CORAL Biospecimens Available

Posted on December 5, 2023

Biospecimens from the Prevention and Early Treatment of Acute Lung Injury (PETAL) Network – Biology and Longitudinal Epidemiology of PETAL COVID-19 Observational Study (BLUE CORAL) study are now available for request.

Data Update for HCT for SCD

Posted on November 13, 2023

Data have been updated for the Hematopoietic Cell Transplant for Sickle Cell Disease (HCT for SCD) study. This update includes an additional year of data.

Data available for request now include allogeneic hematopoietic cell transplants for sickle cell disease (Hb SS and Hb Sβ thalassemia) in the United States from January 1991 to December 2022, as well as follow-up data through May of 2023.

New Study: PETAL-CLOVERS (data and specimens)

Posted on October 13, 2023

A new study, Prevention and Early Treatment of Acute Lung Injury (PETAL) Crystalloid Liberal or Vasopressors Early Resuscitation in Sepsis (CLOVERS), has been posted to BioLINCC. Data and specimens from this study are available for requests.

New Study: BMT CTN-1301 (data)

Posted on September 29, 2023

A new study, Blood and Marrow Clinical Trials Network (BMT CTN) Calcineurin Inhibitor-Free Interventions for Prevention of Graft-versus-Host Disease (1301), has been posted to BioLINCC. Data from this study are available for requests.

New Study: BMT CTN-1302 (data)

Posted on August 31, 2023

A new study, Blood and Marrow Clinical Trials Network (BMT CTN) Multicenter Phase II, Double-blind Placebo Controlled Trial of Maintenance Ixazomib After Allogeneic Hematopoietic Stem Cell Transplantation for High Risk Multiple Myeloma (1302), has been posted to BioLINCC. Data from this study are available for requests.

New Study: CABANA (data)

Posted on July 28, 2023

A new study, Catheter Ablation Versus Antiarrhythmic Drug Therapy for Atrial Fibrillation Trial (CABANA), has been posted to BioLINCC. Data from this study are available for requests.

New Study: BMT CTN-1101 (data)

Posted on July 14, 2023

A new study, Blood and Marrow Clinical Trials Network (BMT CTN) A Multi-Center, Phase III, Randomized Trial of RIC, and Transplantation of (dUCB) Versus HLA-Haplo Related Bone Marrow for Patients with Hematologic Malignancies (1101), has been posted to BioLINCC. Data from this study are available for requests.

New Study: ISCHEMIA/ISCHEMIA-CKD (data)

Posted on July 11, 2023

A new study, International Study of Comparative Health Effectiveness with Medical and Invasive Approaches (ISCHEMIA) and ISCHEMIA - Chronic Kidney Disease (ISCHEMIA - CKD), has been posted to BioLINCC. Data from this study are available for requests.

New Study: PETAL-BLUE CORAL (data)

Posted on July 5, 2023

A new study, Prevention and Early Treatment of Acute Lung Injury (PETAL) Network – Biology and Longitudinal Epidemiology of PETAL COVID-19 Observational Study (BLUE CORAL), has been posted to BioLINCC. Data from this study are available for requests.

Data Update for SPRINT

Posted on June 16, 2023

Data have been updated for the Systolic Blood Pressure Intervention Trial (SPRINT) study. The data now include the Plasma AD ancillary study.

New Study: PF-ILD Proteomics (data)

Posted on June 15, 2023

A new study, Proteomic biomarkers of progressive fibrosing interstitial lung disease: a multicentre cohort analysis (PF-ILD Proteomics), has been posted to BioLINCC. Data from this study are available for requests.

SPRINT Biospecimens Available

Posted on May 15, 2023

Urine specimens from the Systolic Blood Pressure Intervention Trial (SPRINT) study are now available for request.

Data Update for FHS-Gen III

Posted on May 12, 2023

Data have been updated for the Framingham Heart Study (FHS) Third Generation (Gen III), OMNI 2, and New Offspring (NOS) Cohorts. The data now include examination data from the first 3 clinical exams, selected ancillary data and event follow-up and dementia review through 2019. Also included are the OMNI 2 and NOS cohorts.

Data Update for SPRINT

Posted on May 3, 2023

Data have been updated for the Systolic Blood Pressure Intervention Trial (SPRINT) study. The data now include 6 additional ancillary studies including ASK, Heart, FAST, Renal Resistance, Biomarkers, and Raw ABPM.

ARDSNet Biospecimens Available (6 studies)

Posted on April 20, 2023

DNA specimens from 6 ARDSNet studies are now available for request. These studies include: ARDSNet-ALVEOLI, ARDSNet-ALTA, ARDSNet-EDEN, ARDSNet-FACTT, ARDSNet-Omega, and ARDSNet-SAILS.

New Study: WHI-LILAC (data)

Posted on April 20, 2023

A new study, Women’s Health Initiative (WHI) - Life and Longevity After Cancer (LILAC), has been posted to BioLINCC. Data from this study are available for requests.

Data Update for FHS-Cohort

Posted on April 11, 2023

Data have been updated for the Framingham Heart Study-Cohort (FHS-Cohort). The updated data include 5 new datasets and updated food frequency and neuropsychological data.

Digital Clock Drawing Test - Linus Health
Clinic Visit ECG data (MUSE machine)
Clinic Exam ECG Rhythm Interpreted by Clinic MD
Education Level for All Cohorts
Qualitative Errors in Neuropsychological Exams

Data Update for CTSN-SMR

Posted on April 7, 2023

Data have been updated for the Cardiothoracic Surgical Trials Network (CTSN) Evaluation of Outcomes Following Mitral Valve Repair/Replacement in Severe Chronic Ischemic Mitral Regurgitation (SMR) study. This update includes the addition of a concomitant procedures dataset.

Data Update for FHS-Offspring

Posted on April 6, 2023

Data have been updated for the Framingham Heart Study-Offspring (FHS-OS). The data now include data from the first 9 clinical exams, selected ancillary data, and event follow-up through 2019. Also included are the first 4 exams from the OMNI 1 cohort.

Data Update for ARIC Study

Posted on March 22, 2023

Data have been updated for the Atherosclerosis Risk in Communities Study (ARIC) study including cohort follow-up data through 2018, v7 examination data, and data from the Peripheral Neuropathy Testing ancillary study. Now available are data from v1-v7 examination cycles, collated annual follow-up communication data for contact years 2-29, and follow-up for mortality, heart disease, and stroke events through 2018 in addition to 8 ancillary studies.

New Study: BMT CTN-1102 (data)

Posted on March 20, 2023

A new study, Blood and Marrow Clinical Trials Network (BMT CTN) A Multi-Center Biologic Assignment Trial Comparing Allogeneic Hematopoietic Cell Transplant to Hypomethylating Therapy or Best Supportive Care in Patients with Intermediate-2 & High Risk Myelodysplastic Syndrome (1102), has been posted to BioLINCC. Data from this study are available for requests.

Data Update for HCHS-SOL

Posted on February 13, 2023

Data have been updated for the Hispanic Community Health Study / Study of Latinos (HCHS-SOL). The data now include data from the INCA ancillary study.

Data Update for HCT for SCD

Posted on February 10, 2023

Data have been updated for the Hematopoietic Cell Transplant for Sickle Cell Disease (HCT for SCD) study. This update includes an additional year of data.

Data available for request now include allogeneic hematopoietic cell transplants for sickle cell disease (Hb SS and Hb Sβ thalassemia) in the United States from January 1991 to December 2020, as well as follow-up data through 2021.

New Study: DELTA (data)

Posted on January 23, 2023

A new study, Dietary Effects on Lipoproteins and Thrombogenic Activity (DELTA), has been posted to BioLINCC. Data from this study are available for requests.

Data Update for MESA

Posted on January 12, 2023

Data have been updated for the Multi-Ethnic Study of Atherosclerosis (MESA). This update includes the addition of 2 ancillary studies: AS058 Non-Alcoholic Fatty Liver Disease (NAFLD) CT and AS002 Aortic Valvular Calcium (AVC). Some additional Exam 1 variables were also added.

New Study: BMT CTN-1203 (data)

Posted on January 6, 2023

A new study, Blood and Bone Marrow Clinical Trials Network (BMT CTN) A Multi-center Phase II Trial Randomizing Novel Approaches for Graft-versus-Host Disease Prevention Compared to Contemporary Controls (1203), has been posted to BioLINCC. Data from this study are available for requests.

Funding Opportunity: PAR-23-036 Secondary Analysis of Existing Datasets in Heart, Lung, and Blood Diseases and Sleep Disorders (R21)

Posted on December 9, 2022

This Funding Opportunity Announcement (FOA) encourages R21 applications that propose to conduct secondary analyses using existing human datasets in areas relevant to the National Heart, Lung, Blood Diseases and Sleep Disorders Institute (NHLBI) scientific mission. The FOA aims to stimulate the use of existing human datasets to investigate novel scientific ideas, and/or generate new models, systems, tools, or technologies that have the potential for significant impact on biomedical or biobehavioral research. Generation of new primary data is not allowed.

For more information on PAR-23-036 please visit:
https://grants.nih.gov/grants/guide/pa-files/PAR-23-036.html

PETAL-VIOLET Biospecimens Available

Posted on December 6, 2022

Biospecimens from the Prevention and Early Treatment of Acute Lung Injury (PETAL) Clinical Trials Network – Vitamin D to Improve Outcomes by Leveraging Early Treatment (VIOLET) study are now available for request.

New Study: CureSC-SCD (specimens)

Posted on October 25, 2022

A new study, Cure Sickle Cell Hematopoietic Stem Cell Collection (CureSC-SCD), has been posted to BioLINCC. Specimens from this study are available for requests.

AsthmaNet Biospecimens Available (8 studies)

Posted on August 26, 2022

Biospecimens from 8 AsthmaNet studies are now available for request.

This includes the AsthmaNet Proof of Concept Study of Alendronate for Asthma (ALFA), AsthmaNet Azithromycin for Preventing the Development of Upper Respiratory Tract Illness Into Lower Respiratory Tract Symptoms in Children (APRIL) and Oral Corticosteroids for Treating Episodes of Significant Lower Respiratory Tract Symptoms in Children (OCELOT), AsthmaNet Best African American Response to Asthma Drugs (BARD), AsthmaNet Individualized Therapy For Asthma in Toddlers (INFANT) and Acetaminophen Versus Ibuprofen in Children With Asthma (AVICA), AsthmaNet Airway Microbiome in Asthma: Relationships to Asthma Phenotype and Inhaled Corticosteroid Treatment, AsthmaNet Steroids in Eosinophil Negative Asthma (SIENA), AsthmaNet Step-up Yellow Zone Inhaled Corticosteroids to Prevent Exacerbations (STICS), and AsthmaNet Vitamin D Add-on Therapy Enhances Corticosteroid Responsiveness in Asthma (VIDA) studies.

New Study: DISC06 (data and specimens)

Posted on August 25, 2022

A new study, Dietary Intervention Study in Children Follow-Up Study (DISC06), has been posted to BioLINCC. Data and specimens from this study are available for requests.

COAG Biospecimens Available

Posted on July 11, 2022

Biospecimens from the Clarification of Optimal Anticoagulation Through Genetics (COAG) study are now available for request.

PETAL-ROSE Biospecimens Available

Posted on May 6, 2022

Biospecimens from the Prevention and Early Treatment of Acute Lung Injury (PETAL) Network – Reevaluation of Systemic Early Neuromuscular Blockade (ROSE) study are now available for request.

Funding Opportunity: NHLBI R21 RFA-HL-23-018

Posted on March 7, 2022

This funding opportunity is to support meritorious exploratory research relevant to the NHLBI mission using the biospecimen collections that are stored in the NHLBI Biorepository and that are available through BioLINCC. The first application due date is June 21, 2022.

For more information on RFA-HL-23-018 please visit: https://grants.nih.gov/grants/guide/rfa-files/RFA-HL-23-018.html

as well as the FAQs: https://www.nhlbi.nih.gov/grants-and-training/funding-opportunities-and-contacts/RFA-HL-23-018