News
New Study: AsthmaNet-ALFA (data)
Posted on April 2, 2020
A new study, AsthmaNet Proof of Concept Study of Alendronate for Asthma (ALFA), has been posted to BioLINCC. Data from this study are available for requests.
Data Update for FHS-Gen III
Posted on March 25, 2020
Data have been updated for the Framingham Heart Study (FHS) Third Generation (Gen III), OMNI 2, and New Offspring (NOS) Cohorts. The data now include examination data from the first 2 clinical exams, selected ancillary data and event follow-up through 2017. Also included are the OMNI 2 and NOS cohorts.
New Funding Opportunity: NHLBI Big Data Analysis Challenge
Posted on March 24, 2020
The NHLBI is inviting novel Solutions for the NHLBI Big Data Analysis Challenge: Creating New Paradigms for Heart Failure Research. The goal of the challenge is to foster innovation in computational analysis and machine learning approaches utilizing large-scale NHLBI-funded datasets to identify new paradigms in heart failure research. The challenge aims to address the need for new open source disease models that can define sub-categorizations of adult heart failure to serve as a springboard for new research hypotheses and tool development in areas of heart failure research from basic to clinical settings.
NHLBI will award up to a total of $250,000. Up to five (5) winners will be selected, with each winning up to $50,000. The competition period ends at NOON EDT on August 28, 2020.
For more information on this challenge please visit:
https://www.nhlbi.nih.gov/grants-and-training/funding-opportunities-and-contacts/NHLBI-heart-failure-data-challenge
For details on additional funding opportunities go to: Funding Opportunities
New Study: AsthmaNet-INFANT/AVICA (data)
Posted on March 18, 2020
A new study, AsthmaNet Individualized Therapy For Asthma in Toddlers (INFANT) and Acetaminophen Versus Ibuprofen in Children With Asthma (AVICA), has been posted to BioLINCC. Data from this study are available for requests.
New Study: ICARE (data)
Posted on March 17, 2020
A new study, Improved Cardiovascular Risk Reduction to Enhance Rural Primary Care (ICARE), has been posted to BioLINCC. Data from this study are available for requests.
Data Update for FHS-Offspring
Posted on March 10, 2020
Data have been updated for the Framingham Heart Study (FHS) Offspring (OS) and OMNI 1 Cohorts. The data now include Framingham Offspring examination data from the first 9 clinical exams and selected ancillary data and event follow-up through 2016. Also included are the first 4 exams from the OMNI 1 cohort.
Data Update for FHS-Cohort
Posted on March 9, 2020
Data have been updated for the Framingham Heart Study-Cohort (FHS-Cohort). The data now include examination data from the first 32 clinical exams, selected ancillary data, and event follow-up through 2016.
New Study: AsthmaNet-APRIL/OCELOT (data)
Posted on March 2, 2020
A new study, AsthmaNet Azithromycin for Preventing the Development of Upper Respiratory Tract Illness Into Lower Respiratory Tract Symptoms in Children (APRIL) and Oral Corticosteroids for Treating Episodes of Significant Lower Respiratory Tract Symptoms in Children (OCELOT), has been posted to BioLINCC. Data from this study are available for requests.
New Study: AsthmaNet-VIDA (data)
Posted on February 21, 2020
A new study, AsthmaNet Vitamin D Add-on Therapy Enhances Corticosteroid Responsiveness in Asthma (VIDA), has been posted to BioLINCC. Data from this study are available for requests.
New Study: AsthmaNet-SIENA (data)
Posted on February 11, 2020
A new study, AsthmaNet Steroids in Eosinophil Negative Asthma (SIENA), has been posted to BioLINCC. Data from this study are available for requests.
New Study: AsthmaNet-STICS (data)
Posted on February 4, 2020
A new study, AsthmaNet Step-up Yellow Zone Inhaled Corticosteroids to Prevent Exacerbations (STICS), has been posted to BioLINCC. Data from this study are available for requests.
New Study: AsthmaNet-BARD (data)
Posted on January 27, 2020
A new study, AsthmaNet Best African American Response to Asthma Drugs (BARD), has been posted to BioLINCC. Data from this study are available for requests.
New Study: ROC-PROHS (data)
Posted on January 16, 2020
A new study, Resuscitation Outcomes Consortium (ROC) Prehospital Resuscitation on Helicopter Study (PROHS), has been posted to BioLINCC. Data from this study are available for requests.
New Study: ROC-PART (data)
Posted on December 27, 2019
A new study, Resuscitation Outcomes Consortium (ROC) Pragmatic Trial of Airway Management in Out-of-Hospital Cardiac Arrest (PART), has been posted to BioLINCC. Data from this study are available for requests.
Data Update for CARDIA
Posted on December 6, 2019
Data have been updated for the CARDIA study (Coronary Artery Risk Development in Young Adults). Year 30 exam data and outcomes data with follow-up through 2016 are now available.
Data Update for MESA
Posted on November 15, 2019
Data have been updated for the Multi-Ethnic Study of Atherosclerosis (MESA) to include ancillary studies #047 and #075 on Vitamin D, #195 on Fatty Acid, and #200 on Total FFA. Now available are data through exam 5, follow-up event data through year 10, and data from eleven ancillary studies.
Data Update for ARIC Study
Posted on November 14, 2019
Data have been updated for the Atherosclerosis Risk in Communities Study (ARIC) study including cohort follow-up data through 2015 . Now available are data from v1-v5 examination cycles, collated annual follow-up communication data for contact years 2-26, and follow-up for mortality, heart disease, and stroke events through 2015 in addition to 7 ancillary studies.
New Study: BMT CTN-0501 (data)
Posted on November 1, 2019
A new study, Blood and Marrow Transplant Clinical Trials Network (BMT CTN) Multi-center, Open Label, Randomized Trial Comparing Single Versus Double Umbilical Cord Blood (UCB) Transplantation in Pediatric Patients With High Risk Leukemia and Myelodysplasia (0501), has been posted to BioLINCC. Data from this study are available for requests.
New Study: BMT CTN-0901 (data)
Posted on October 10, 2019
A new study, Blood and Marrow Transplant Clinical Trials Network (BMT CTN) A Randomized, Multi-Center, Phase III Study of Allogeneic Stem Cell Transplantation Comparing Regimen Intensity in Patients with Myelodysplastic Syndrome or Acute Myeloid Leukemia (0901), has been posted to BioLINCC. Data from this study are available for requests.
New Study: CCTRN-PACE (data)
Posted on September 17, 2019
A new study, Cardiovascular Cell Therapy Research Network (CCTRN) Clinical and MR Imaging Assessments in Patients With Intermittent Claudication Following Injection of Bone Marrow Derived ALDH Bright Cells (PACE), has been posted to BioLINCC. Data from this study are available for requests.
Funding Opportunities Added
Posted on August 30, 2019
New information regarding secondary data and/or biospecimen analysis funding opportunities from NHLBI, NIDDK, and FDA has been added to the funding opportunities page. These NIH Exploratory (R21) grant funding opportunities may be applicable to research using BioLINCC resources. Additionally included is an NHLBI released Notice of Special Interest (NOSI) on Data Science R01 applications. Please see the funding opportunities page, which includes links to the NIH grant announcements, for more information.
New Study: WRAP-IPF (data)
Posted on August 29, 2019
A new study, Weighing Risks and Benefits of Laparoscopic Anti-Reflux Surgery in Patients With Idiopathic Pulmonary Fibrosis (WRAP-IPF), has been posted to BioLINCC. Data from this study are available for requests.
New Study: CCTRN-FOCUS (data)
Posted on August 26, 2019
A new study, Cardiovascular Cell Therapy Research Network (CCTRN) Randomized, Controlled, Phase II, Double-Blind Trial of Intramyocardial Injection of Autologous Bone Marrow Mononuclear Cells Under Electromechanical Guidance for Patients With Chronic Ischemic Heart Disease and Left Ventricular Dysfunction (FOCUS), has been posted to BioLINCC. Data from this study are available for requests.
New Study: REDS III (data)
Posted on August 23, 2019
A new study, Recipient Epidemiology and Donor Evaluation Study-III (REDS-III) Vein to Vein Databases, has been posted to BioLINCC. Data from this study are available for requests.
New Study: WHI-CTOS (data)
Posted on August 16, 2019
A new study, Women's Health Initiative: Clinical Trial and Observational Study (WHI-CTOS), has been posted to BioLINCC. This study incorporates prior releases of WHI-CT and WHI-OS data into one unified study.
Data from this study are available for requests.
New Study: GUIDE-IT (data)
Posted on July 31, 2019
A new study, Guiding Evidence Based Therapy Using Biomarker Intensified Treatment in Heart Failure (GUIDE-IT), has been posted to BioLINCC. Data from this study are available for requests.
New Study: THAPCA-IH (data)
Posted on July 31, 2019
A new study, Therapeutic Hypothermia After Pediatric Cardiac Arrest (In-Hospital) (THAPCA-IH), has been posted to BioLINCC. Data from this study are available for requests.
New Study: BMT CTN-0301 (data)
Posted on July 8, 2019
A new study, Blood and Marrow Clinical Trials Network (BMT CTN) Fludarabine-based Conditioning for Severe Aplastic Anemia (0301), has been posted to BioLINCC. Data from this study are available for requests.
Data Update for SPIROMICS
Posted on June 28, 2019
Data have been updated for the Subpopulations and Intermediate Markers in COPD Study (SPIROMICS). Now available are data from the SPIROMICS I main study as well as the SPIROMICS Bridge phone call follow-up period (period between SPIROMICS I NIH contract and SPIROMICS II grant).
New Study: SPRINT (data and specimens)
Posted on June 24, 2019
A new study, Systolic Blood Pressure Intervention Trial (SPRINT), has been posted to BioLINCC. Data and specimens from this study are available for requests.
The SPRINT-POP data, based on the primary outcome paper and previously available for request through the BioLINCC website, have been incorporated into this SPRINT full study data release.
Data Update for Intermacs
Posted on May 13, 2019
Data have been updated for Interagency Registry for Mechanically Assisted Circulatory Support (Intermacs) to include data from the Medical Arm of Mechanical Circulatory Support (MedaMACS) Study and additional data from the Intermacs and Pedimacs studies.
New Study: CCTRN-LateTIME (data)
Posted on May 7, 2019
A new study, Cardiovascular Cell Therapy Research Network (CCTRN) A Phase II, Randomized, Controlled, Double-Blind Pilot Trial Evaluating the Safety and Effect of Administration of Bone Marrow Mononuclear Cells Two to Three Weeks Following Acute Myocardial Infarction (LateTIME), has been posted to BioLINCC. Data from this study are available for requests.
New Study: CCTRN-TIME (data)
Posted on May 7, 2019
A new study, Cardiovascular Cell Therapy Research Network (CCTRN) Transplantation in Myocardial Infarction Evaluation (TIME) Protocol: A Phase II, Randomized, Controlled, Double-Blind Trial Evaluating the Effect of Timing on the Administration of Bone Marrow Mononuclear Cells (BMMNCs) Versus Placebo in Patients With Acute Myocardial Infarction, has been posted to BioLINCC. Data from this study are available for requests.
Data Update for ARIC Study
Posted on May 3, 2019
Data have been updated for the Atherosclerosis Risk in Communities Study (ARIC) study to include two additional ancillary studies: adjudicated cancer outcomes (through 2012) and additional biomarkers from stored V2 blood . Now available are data from v1-v5 examination cycles, collated annual follow-up communication data for contact years 2-26, and follow-up for mortality, heart disease, and stroke events through 2014 in addition to 7 ancillary studies.
Data Update for MESA
Posted on April 30, 2019
Data have been updated for the Multi-Ethnic Study of Atherosclerosis (MESA) to include ancillary studies #205 on Brachial IMT and #113 on Exam 5 Sleep. Now available are data through exam 5, follow-up event data through year 10, and data from eight ancillary studies.
Novel Evaluation of GenTAC Images is Available
Posted on November 2, 2017
The Imaging Core Lab of the National Registry of Genetically Triggered Thoracic Aortic Aneurysms (GenTAC) is now considering applications from researchers who have obtained GenTAC data through BioLINCC and who wish to have additional or novel evaluation of GenTAC images beyond the image readings obtained under the original GenTAC study protocol. The application form, instructions, and contact information for the Imaging Core Lab will be made available for request upon approval and fulfillment of a GenTAC data request through BioLINCC.
New BioLINCC Manuscript
Posted on June 15, 2017
A new open-access paper about BioLINCC metrics and results is now available on PLOS ONE:
Giffen CA, Wagner EL, Adams JT, Hitchcock DM, Welniak LA, Brennan SP, Carroll LE. “Providing researchers with online access to NHLBI biospecimen collections: The results of the first six years of the NHLBI BioLINCC program”.