News


Data Update for ARIC Study

Data have been updated for the Atherosclerosis Risk in Communities Study (ARIC) study including cohort follow-up data through 2019, annual follow-up communication data for years 30 and 31, and data from the Brain MRI ancillary study, the ApoE ancillary study, the GDF-15 v6 ancillary study, and nine v7 ancillary studies. Now available are data from v1-v7 examination cycles, collated annual follow-up communication data for contact years 2-31, and follow-up for mortality, heart disease, and stroke events through 2019 in addition to 20 ancillary studies.


New Study: TRIM (data)

A new study, Trial of Roflumilast in Asthma Management (TRIM), has been posted to BioLINCC. Data from this study are available for requests.


New Study: SCDIC Registry (data)

A new study, Sickle Cell Disease Implementation Consortium (SCDIC) Sickle Cell Disease Patient Registry, has been posted to BioLINCC. Data from this study are available for requests.


New Study: CCTRN-CONCERT HF (data)

A new study, Cardiovascular Cell Therapy Research Network (CCTRN) A Phase II, Randomized, Placebo-Controlled Study of the Safety, Feasibility, & Efficacy of Autologous Mesenchymal Stem Cells & C-kit+ Cardiac Stem Cells, Alone or in Combination, Administered Transendocardially in Subjects With Ischemic HF (CONCERT HF), has been posted to BioLINCC. Data from this study are available for requests.


New Study: CTSN-NP (data)

A new study, Cardiothoracic Surgical Trials Network (CTSN) Neuroprotection in Patients Undergoing Aortic Valve Replacement (NP), has been posted to BioLINCC. Data from this study are available for requests.


New Study: BMT CTN-1502 (data)

A new study, Blood and Marrow Clinical Trials Network (BMT CTN) Optimizing Haploidentical Aplastic Anemia Transplantation (CHAMP 1502), has been posted to BioLINCC. Data from this study are available for requests.


New Study: PETAL-FIRE CORAL (data and specimens)

A new study, Prevention and Early Treatment of Acute Lung Injury (PETAL) Network – Functional, imaging, and respiratory evaluation in CORAL (FIRE CORAL), has been posted to BioLINCC. Data and specimens from this study are available for requests.


Data Update for DISC

Data have been updated for the Dietary Intervention Study in Children (DISC). This update includes the addition of metabolomics and hormone data.


New Study: HFN-LIFE (data)

A new study, Heart Failure Network (HFN) - EntrestoTM (LCZ696) In Advanced Heart Failure (LIFE), has been posted to BioLINCC. Data from this study are available for requests.


Data Update for FHS-Gen III

Data have been updated for the Framingham Heart Study (FHS) Third Generation (Gen III), OMNI 2, and New Offspring (NOS) Cohorts. This update includes the addition of Brain MRI data.


Data Update for FHS-Offspring

Data have been updated for the Framingham Heart Study-Offspring (FHS-OS). This update includes the addition of Brain MRI data.


New Study: CTSN-MMR (data)

A new study, Cardiothoracic Surgical Trials Network (CTSN) Surgical Interventions for Moderate Ischemic Mitral Regurgitation (MMR), has been posted to BioLINCC. Data from this study are available for requests.


Data Update for PETAL-ROSE

Data have been updated for the Prevention and Early Treatment of Acute Lung Injury (PETAL) Network – Reevaluation of Systemic Early Neuromuscular Blockade (ROSE) study. This update includes Long Term Outcome data.


PETAL-BLUE CORAL Biospecimens Available

Biospecimens from the Prevention and Early Treatment of Acute Lung Injury (PETAL) Network – Biology and Longitudinal Epidemiology of PETAL COVID-19 Observational Study (BLUE CORAL) study are now available for request.


Data Update for HCT for SCD

Data have been updated for the Hematopoietic Cell Transplant for Sickle Cell Disease (HCT for SCD) study. This update includes an additional year of data.

Data available for request now include allogeneic hematopoietic cell transplants for sickle cell disease (Hb SS and Hb Sβ thalassemia) in the United States from January 1991 to December 2022, as well as follow-up data through May of 2023.


New Study: PETAL-CLOVERS (data and specimens)

A new study, Prevention and Early Treatment of Acute Lung Injury (PETAL) Crystalloid Liberal or Vasopressors Early Resuscitation in Sepsis (CLOVERS), has been posted to BioLINCC. Data and specimens from this study are available for requests.


New Study: BMT CTN-1301 (data)

A new study, Blood and Marrow Clinical Trials Network (BMT CTN) Calcineurin Inhibitor-Free Interventions for Prevention of Graft-versus-Host Disease (1301), has been posted to BioLINCC. Data from this study are available for requests.


New Study: BMT CTN-1302 (data)

A new study, Blood and Marrow Clinical Trials Network (BMT CTN) Multicenter Phase II, Double-blind Placebo Controlled Trial of Maintenance Ixazomib After Allogeneic Hematopoietic Stem Cell Transplantation for High Risk Multiple Myeloma (1302), has been posted to BioLINCC. Data from this study are available for requests.


New Study: CABANA (data)

A new study, Catheter Ablation Versus Antiarrhythmic Drug Therapy for Atrial Fibrillation Trial (CABANA), has been posted to BioLINCC. Data from this study are available for requests.


New Study: BMT CTN-1101 (data)

A new study, Blood and Marrow Clinical Trials Network (BMT CTN) A Multi-Center, Phase III, Randomized Trial of RIC, and Transplantation of (dUCB) Versus HLA-Haplo Related Bone Marrow for Patients with Hematologic Malignancies (1101), has been posted to BioLINCC. Data from this study are available for requests.


New Study: ISCHEMIA/ISCHEMIA-CKD (data)

A new study, International Study of Comparative Health Effectiveness with Medical and Invasive Approaches (ISCHEMIA) and ISCHEMIA - Chronic Kidney Disease (ISCHEMIA - CKD), has been posted to BioLINCC. Data from this study are available for requests.


New Study: PETAL-BLUE CORAL (data)

A new study, Prevention and Early Treatment of Acute Lung Injury (PETAL) Network – Biology and Longitudinal Epidemiology of PETAL COVID-19 Observational Study (BLUE CORAL), has been posted to BioLINCC. Data from this study are available for requests.


Data Update for SPRINT

Data have been updated for the Systolic Blood Pressure Intervention Trial (SPRINT) study. The data now include the Plasma AD ancillary study.


New Study: PF-ILD Proteomics (data)

A new study, Proteomic biomarkers of progressive fibrosing interstitial lung disease: a multicentre cohort analysis (PF-ILD Proteomics), has been posted to BioLINCC. Data from this study are available for requests.


Funding Opportunity: PAR-23-036 Secondary Analysis of Existing Datasets in Heart, Lung, and Blood Diseases and Sleep Disorders (R21)

This Funding Opportunity Announcement (FOA) encourages R21 applications that propose to conduct secondary analyses using existing human datasets in areas relevant to the National Heart, Lung, Blood Diseases and Sleep Disorders Institute (NHLBI) scientific mission. The FOA aims to stimulate the use of existing human datasets to investigate novel scientific ideas, and/or generate new models, systems, tools, or technologies that have the potential for significant impact on biomedical or biobehavioral research. Generation of new primary data is not allowed.

For more information on PAR-23-036 please visit:
https://grants.nih.gov/grants/guide/pa-files/PAR-23-036.html


PETAL-VIOLET Biospecimens Available

Biospecimens from the Prevention and Early Treatment of Acute Lung Injury (PETAL) Clinical Trials Network – Vitamin D to Improve Outcomes by Leveraging Early Treatment (VIOLET) study are now available for request.


New Study: CureSC-SCD (specimens)

A new study, Cure Sickle Cell Hematopoietic Stem Cell Collection (CureSC-SCD), has been posted to BioLINCC. Specimens from this study are available for requests.


AsthmaNet Biospecimens Available (8 studies)

Biospecimens from 8 AsthmaNet studies are now available for request.

This includes the AsthmaNet Proof of Concept Study of Alendronate for Asthma (ALFA), AsthmaNet Azithromycin for Preventing the Development of Upper Respiratory Tract Illness Into Lower Respiratory Tract Symptoms in Children (APRIL) and Oral Corticosteroids for Treating Episodes of Significant Lower Respiratory Tract Symptoms in Children (OCELOT), AsthmaNet Best African American Response to Asthma Drugs (BARD), AsthmaNet Individualized Therapy For Asthma in Toddlers (INFANT) and Acetaminophen Versus Ibuprofen in Children With Asthma (AVICA), AsthmaNet Airway Microbiome in Asthma: Relationships to Asthma Phenotype and Inhaled Corticosteroid Treatment, AsthmaNet Steroids in Eosinophil Negative Asthma (SIENA), AsthmaNet Step-up Yellow Zone Inhaled Corticosteroids to Prevent Exacerbations (STICS), and AsthmaNet Vitamin D Add-on Therapy Enhances Corticosteroid Responsiveness in Asthma (VIDA) studies.


New Study: DISC06 (data and specimens)

A new study, Dietary Intervention Study in Children Follow-Up Study (DISC06), has been posted to BioLINCC. Data and specimens from this study are available for requests.


COAG Biospecimens Available

Biospecimens from the Clarification of Optimal Anticoagulation Through Genetics (COAG) study are now available for request.


PETAL-ROSE Biospecimens Available

Biospecimens from the Prevention and Early Treatment of Acute Lung Injury (PETAL) Network – Reevaluation of Systemic Early Neuromuscular Blockade (ROSE) study are now available for request.


Funding Opportunity: NHLBI R21 RFA-HL-23-018

This funding opportunity is to support meritorious exploratory research relevant to the NHLBI mission using the biospecimen collections that are stored in the NHLBI Biorepository and that are available through BioLINCC. The first application due date is June 21, 2022.

For more information on RFA-HL-23-018 please visit: https://grants.nih.gov/grants/guide/rfa-files/RFA-HL-23-018.html

as well as the FAQs: https://www.nhlbi.nih.gov/grants-and-training/funding-opportunities-and-contacts/RFA-HL-23-018

To view RFA-HL-23-018 funded projects please visit NIH RePORTER