Bypass Angioplasty Revascularization Investigation (BARI)
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Accession Number
HLB00610707a
Study Type
Clinical Trial
Collection Type
Open BioLINCC Study
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Study Period
1987-2004
NHLBI Division
DCVS
Dataset(s) Last Updated
July 17, 2020
Clinical Trial URLs
https://clinicaltrials.gov/ct/show/NCT00000462?order=3
Primary Publication URLs
N/A
Consent
Commercial Use Data Restrictions No
Data Restrictions Based On Area Of Research No
Available Data
The database contains a subset of the trial data and includes baseline characteristics and 10 year followup information on all 1,829 patients. Endpoints include subsequent revascularization, new myocardial infarction or death.
Objectives
The BARI (Bypass Angioplasty Revascularization Investigation) trial was designed to compare survival in patients randomized to receive either percutaneous transluminal coronary balloon angioplasty (PTCA) or coronary artery bypass grafting (CABG).
Background
Angioplasty and bypass surgery have been compared in numerous studies, but long-term clinical outcomes are limited. Symptomatic patients with multivessel coronary artery disease (n = 1,829) were randomly assigned to initial treatment with PTCA or CABG and followed up for an average of 10.4 years.
Conclusions
There was no significant long-term disadvantage regarding mortality or myocardial infarction associated with an initial strategy of PTCA compared with CABG. Among patients with treated diabetes, CABG conferred long-term survival benefit, whereas the 2 initial strategies were equivalent regarding survival for patients without diabetes.
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Resources Available
Study Datasets OnlyStudy Documents
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