Income disparity and incident cardiovascular disease in older Americans.

Pubmed ID: 34320387

Journal: Progress in cardiovascular diseases

Publication Date: March 1, 2022

MeSH Terms: Humans, Male, Female, Aged, Cardiovascular Diseases, Risk Factors, United States, Cohort Studies, Heart Failure, Incidence, Medicare

Grants: R01 HL085561, R01 HL097047

Authors: Ahmed A, Fonarow GC, Deedwania P, Allman RM, Morgan CJ, Alagiakrishnan K, Ahmed AA, Lam PH, Faselis C, Safren L, Brar V, Sheikh FH

Cite As: Faselis C, Safren L, Allman RM, Lam PH, Brar V, Morgan CJ, Ahmed AA, Deedwania P, Alagiakrishnan K, Sheikh FH, Fonarow GC, Ahmed A. Income disparity and incident cardiovascular disease in older Americans. Prog Cardiovasc Dis 2022 Mar-Apr;71:92-99. Epub 2021 Jul 25.

Studies:

Abstract

OBJECTIVE: To examine the association between income and cardiovascular disease (CVD) in community-dwelling older adults. METHODS: Of the 5795 Medicare-eligible community-dwelling older Americans aged 65-100 years in the Cardiovascular Health Study (CHS), 4518 (78%) were free of baseline CVD, defined as heart failure, acute myocardial infarction, stroke, or peripheral arterial disease. Of them, 1846 (41%) had lower income, defined as a total annual household income <$16,000. Using propensity scores for lower income, estimated for each of the 4518 participants, we assembled a matched cohort of 1078 pairs balanced on 42 baseline characteristics. Outcomes included centrally adjudicated incident CVD and mortality. RESULTS: Matched participants (n = 2156) had a mean age of 73 years, 63% were women, and 13% African American. During an overall follow-up of 23 years, incident CVD, all-cause mortality and the combined endpoint of incident CVD or mortality occurred in 1094 (51%), 1726 (80%) and 1867 (87%) individuals, respectively. Compared with the higher income group, hazard ratio (HR) for time to the first occurrence of incident CVD in the lower income group was 1.16 with a 95% confidence interval (CI) of 1.03 to 1.31. A lower income was also associated with a significantly higher risk of all-cause mortality (HR, 1.19; 95% CI, 1.08-1.30), and consequently a higher risk of the combined endpoint of incident CVD or death (HR, 1.20; 95% CI, 1.09-1.31). CONCLUSION: Among community-dwelling older Americans free of baseline CVD, an annual household income <$16,000 is independently associated with significantly higher risks of new-onset CVD and death.