New directions in dietary studies and heart disease: the National Heart, Lung and Blood Institute sponsored Multicenter Study of Diet Effects on Lipoproteins and Thrombogenic Activity.

Pubmed ID: 7598013

Journal: Advances in experimental medicine and biology

Publication Date: Jan. 1, 1995

MeSH Terms: Humans, Male, Adult, Female, United States, Heart Diseases, Double-Blind Method, Lipids, National Institutes of Health (U.S.), Thrombosis, Lipoproteins, Dietary Fats, Cross-Over Studies, Blood Chemical Analysis, Clinical Protocols

Authors: Ginsberg HN

Cite As: Ginsberg HN. New directions in dietary studies and heart disease: the National Heart, Lung and Blood Institute sponsored Multicenter Study of Diet Effects on Lipoproteins and Thrombogenic Activity. Adv Exp Med Biol 1995;369:241-7.

Studies:

Abstract

The National Heart, Blood and Lung Institute-sponsored DELTA study is the first collaborative, multicenter diet study to utilize standardized protocols to feed specific diets to study participants. In the first study, the investigators are focusing on the effects of reducing dietary saturated fat on plasma lipids, lipoproteins, and thrombogenic activity. Future studies will attempt to address important diet/public health questions dealing with high carbohydrate vs. high monounsaturated fat diets, and the cholesterol raising activity of specific saturated fatty acids. Moreover, DELTA will be an invaluable model for other multicenter diet studies.