Pubmed ID: 34735903

Pubmed Central ID: PMC8671319

Journal: Journal of critical care

Publication Date: Feb. 1, 2022

MeSH Terms: Humans, Positive-Pressure Respiration, Respiratory Insufficiency, Hypoxia

Grants: F32 GM133061, T32 HL007035, K23 HL153482

Authors: Walkey AJ, Bosch NA, Lee MM, LeSieur MN, Law AC

Cite As: Bosch NA, Lee MM, LeSieur MN, Law AC, Walkey AJ. Death due to irreversible hypoxemic respiratory failure in ARDSnet clinical trials. J Crit Care 2022 Feb;67:85-87. Epub 2021 Oct 29.

Studies:

• Acute Respiratory Distress Network (ARDSNet) Studies 01 and 03 Lower versus higher tidal volume, ketoconazole treatment and lisofylline treatment (ARMA/KARMA/LARMA)
• Acute Respiratory Distress Network (ARDSNet) Studies 06 and 08 Prospective, Randomized, Multicenter Trial of Aerosolized Albuterol Versus Placebo for the Treatment of Acute Lung Injury (ALTA)
• Acute Respiratory Distress Network (ARDSNet) Studies 07 and 08 Prospective, Randomized, Blinded, Placebo-controlled, Multi-center Trial of Omega-3 Fatty Acid, Gamma-Linolenic Acid, and Anti-Oxidant Supplementation in the Management of Acute Lung Injury or Acute Respiratory Distress Syndrome (Omega)
• Acute Respiratory Distress Network (ARDSNet) Studies 07, 08, 09, 11, and 12 Early Versus Delayed Enteral Feeding to Treat People with Acute Lung Injury or Acute Respiratory Distress Syndrome (EDEN)
• Acute Respiratory Distress Network (ARDSNet) Studies 10 and 12 Statins for Acutely Injured Lungs from Sepsis (SAILS)
• Acute Respiratory Distress Network (ARDSNet) Study 02 Late Steroid Rescue Study (LaSRS)
• Acute Respiratory Distress Network (ARDSNet) Study 04 Assessment of Low tidal Volume and elevated End-expiratory volume to Obviate Lung Injury (ALVEOLI)
• Acute Respiratory Distress Network (ARDSNet) Study 05 Fluid and Catheter Treatment Trial (FACTT)