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BioLINCC Program Literature
No (5)
Study
A Case Controlled Etiologic Study of Sarcoidosis (ACCESS) (30)
Action to Control Cardiovascular Risk in Diabetes (ACCORD) (155)
Activity Counseling Trial (ACT) (3)
Acute Coronary Syndrome Quality Improvement in Kerala (ACS-QUIK) Cluster Randomized, Stepped Wedge Multi-center Implementation of a Locally-Developed Quality Improvement Toolkit (3)
Acute Respiratory Distress Network (ARDSNet) Studies 01 and 03 Lower versus higher tidal volume, ketoconazole treatment and lisofylline treatment (ARMA/KARMA/LARMA) (36)
Acute Respiratory Distress Network (ARDSNet) Studies 06 and 08 Prospective, Randomized, Multicenter Trial of Aerosolized Albuterol Versus Placebo for the Treatment of Acute Lung Injury (ALTA) (29)
Acute Respiratory Distress Network (ARDSNet) Studies 07 and 08 Prospective, Randomized, Blinded, Placebo-controlled, Multi-center Trial of Omega-3 Fatty Acid, Gamma-Linolenic Acid, and Anti-Oxidant Supplementation in the Management of Acute Lung Injury or Acute Respiratory Distress Syndrome (Omega) (9)
Acute Respiratory Distress Network (ARDSNet) Studies 07, 08, 09, 11, and 12 Early Versus Delayed Enteral Feeding to Treat People with Acute Lung Injury or Acute Respiratory Distress Syndrome (EDEN) (20)
Acute Respiratory Distress Network (ARDSNet) Studies 10 and 12 Statins for Acutely Injured Lungs from Sepsis (SAILS) (29)
Acute Respiratory Distress Network (ARDSNet) Study 02 Late Steroid Rescue Study (LaSRS) (12)
Acute Respiratory Distress Network (ARDSNet) Study 04 Assessment of Low tidal Volume and elevated End-expiratory volume to Obviate Lung Injury (ALVEOLI) (38)
Acute Respiratory Distress Network (ARDSNet) Study 05 Fluid and Catheter Treatment Trial (FACTT) (72)
Anti-HIV Immunoglobulin in Prevention of Maternal-Fetal HIV Transmission: Pediatric AIDS Clinical Trials Group protocol 185 (PACTG) (1)
Antiarrhythmics Versus Implantable Defibrillators (AVID) (5)
Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) (36)
Aspirin-Myocardial Infarction Study (AMIS) (7)
Asthma Clinical Research Network (ACRN) Salmeterol Off CorticoSteroids (SOCS) and Salmeterol Inhaled Corticosteroids (SLIC) (1)
Asthma Clinical Research Network Trial (ACRN) - Best Adjustment Strategy for Asthma in Long Term (BASALT) and Tiotropium Bromide as an Alternative to Increased Inhaled Corticosteroid in Patients Inadequately Controlled on a Lower Dose of Inhaled Corticosteroid (TALC) (2)
AsthmaNet Azithromycin for Preventing the Development of Upper Respiratory Tract Illness Into Lower Respiratory Tract Symptoms in Children (APRIL) and Oral Corticosteroids for Treating Episodes of Significant Lower Respiratory Tract Symptoms in Children (OCELOT) (2)
AsthmaNet Best African American Response to Asthma Drugs (BARD) (1)
AsthmaNet Individualized Therapy For Asthma in Toddlers (INFANT) and Acetaminophen Versus Ibuprofen in Children With Asthma (AVICA) (2)
Atherosclerosis Risk in Communities (ARIC) (137)
Atherosclerosis Risk in Communities Study (ARIC) (255)
Atherothrombosis Intervention in Metabolic Syndrome with Low HDL/High Triglyceride and Impact on Global Health Outcomes (AIM-HIGH) (6)
Atrial Fibrillation Follow-Up Investigation of Rhythm Management (AFFIRM) (42)
Beta-Blocker Evaluation in Survival Trial (BEST) (40)
Beta-Blocker Heart Attack Trial (BHAT) (5)
Blood and Marrow Clinical Trials Network (BMT CTN) A Phase III Randomized, Multicenter Trial Comparing Sirolimus/Tacrolimus With Tacrolimus/Methotrexate as Graft-versus-Host Disease Prophylaxis After HLA-Matched, Related Peripheral Blood Stem Cell Transplantation (0402) (1)
Blood and Marrow Clinical Trials Network (BMT CTN) Comparing Peripheral Blood Stem Cell Transplantation Versus Bone Marrow Transplantation in Individuals With Hematologic Cancers (0201) (2)
Blood and Marrow Clinical Trials Network (BMT CTN) Prospective Multi-Center Cohort for the Evaluation of Biomarkers Predicting Risk of Complications and Mortality Following Allogeneic HCT (1202) (1)
Blood and Marrow Transplant Clinical Trials Network (BMT CTN) Phase II Randomized Trial Evaluating Etanercept, Mycophenolate Mofetil, Denileukin Diftitox, and Pentostatin in Combination With Corticosteroids for Initial Systemic Treatment of Acute Graft-Versus-Host Disease (0302) (1)
Bogalusa Heart Study (BHS) (6)
Bypass Angioplasty Revascularization Investigation (BARI) (6)
Bypass Angioplasty Revascularization Investigation in Type 2 Diabetes (BARI 2D) (19)
Cardiac Arrhythmia Suppression Trial (CAST) (3)
Cardiothoracic Surgical Trials Network (CTSN) Rate Control Versus Rhythm Control For Postoperative Atrial Fibrillation (POAF) (1)
Cardiothoracic Surgical Trials Network (CTSN) and Cardiovascular Cell Therapy Research Network (CCTRN) Left Ventricular Assist Device Therapy: Exploring the Effect of Intramyocardial Injection of Mesenchymal Precursor Cells on Myocardial Function (LVAD) (1)
Cardiovascular Cell Therapy Research Network (CCTRN) Randomized, Controlled, Phase II, Double-Blind Trial of Intramyocardial Injection of Autologous Bone Marrow Mononuclear Cells Under Electromechanical Guidance for Patients With Chronic Ischemic Heart Disease and Left Ventricular Dysfunction (FOCUS) (1)
Cardiovascular Health Study (CHS) (163)
Cardiovascular Outcomes in Renal Atherosclerotic Lesions (CORAL) (1)
Catheter Ablation Versus Antiarrhythmic Drug Therapy for Atrial Fibrillation Trial (CABANA) (1)
Childhood Asthma Management Program (CAMP) (6)
Childhood Asthma Research and Education (CARE) Network Trial - Acute Intervention Management Strategies (AIMS) (1)
Clarification of Optimal Anticoagulation Through Genetics (COAG) (4)
Claudication: Exercise Versus Endoluminal Revascularization (CLEVER) (2)
Clinical Study of Intermittent Positive Pressure Breathing (IPPB) (1)
Colchicine Coronavirus SARS-CoV2 Trial (COLCORONA) (1)
Collaboration Among Pharmacists and Physicians to Improve Outcomes Now (CAPTION) (1)
Cooperative Study of Sickle Cell Disease (CSSCD) (23)
Cord Blood Transplantation Study (COBLT) (14)
Coronary Artery Risk Development in Young Adults (CARDIA) (88)
Coronary Artery Surgery Study (CASS) (3)
Dietary Approaches to Stop Hypertension (DASH) (9)
Dietary Approaches to Stop Hypertension - Sodium Study (DASH-Sodium) (25)
Dietary Effects on Lipoproteins and Thrombogenic Activity (DELTA) (17)
Dietary Intervention Study in Children (DISC) (2)
Dietary Intervention Study in Children Follow-Up Study (DISC06) (1)
Digitalis Investigation Group (DIG) (86)
Enhancing Recovery in Coronary Heart Disease Patients (ENRICHD) (9)
Evaluation Study of Congestive Heart Failure and Pulmonary Artery Catheterization Effectiveness (ESCAPE) (48)
Framingham Heart Study (FHS) (35)
Framingham Heart Study (FHS) Offspring (OS) and OMNI 1 Cohorts (175)
Framingham Heart Study (FHS) Third Generation (Gen III), OMNI 2, and New Offspring (NOS) Cohorts (12)
Framingham Heart Study-Cohort (FHS-Cohort) (188)
Functional Outcomes in Cardiovascular Patients Undergoing Surgical Hip Fracture Repair (FOCUS) (1)
Global Health Centers of Excellence (GHCoE) Argentina (3)
Global Health Centers of Excellence (GHCoE) Guatemala (2)
Global Health Centers of Excellence (GHCoE) New Delhi (3)
Global Health Centers of Excellence (GHCoE) South Africa (2)
Guiding Evidence Based Therapy Using Biomarker Intensified Treatment in Heart Failure (GUIDE-IT) (2)
Healthy Communities Study (HCS) (1)
Heart Failure Network (HFN) CARdiorenal REScue Study in Acute Decompensated Heart Failure (CARRESS) (12)
Heart Failure Network (HFN) Diuretic Optimization Strategies Evaluation in Acute Heart Failure (DOSE AHF) (14)
Heart Failure Network (HFN) Functional Impact of GLP-1 for Heart Failure Treatment (FIGHT) (1)
Heart Failure Network (HFN) Inorganic Nitrite Delivery to Improve Exercise Capacity in HFpEF (INDIE) (1)
Heart Failure Network (HFN) Nitrate's Effect on Activity Tolerance in Heart Failure with Preserved Ejection Fraction (NEAT) (3)
Heart Failure Network (HFN) Oral Iron Repletion Effects on Oxygen Uptake in Heart Failure (IRONOUT) (1)
Heart Failure Network (HFN) Phosphodiesterase-5 Inhibition to Improve Clinical Status and Exercise Capacity in Diastolic Heart Failure (RELAX) (7)
Heart Failure Network (HFN) Renal Optimization Strategies Evaluation in Acute Heart Failure and Reliable Evaluation of Dyspnea (ROSE) (12)
Heart Failure: A Controlled Trial Investigating Outcomes of Exercise Training (HF-ACTION) (20)
Hemochromatosis and Iron Overload Screening Study (HEIRS) (8)
High Frequency Ventilation in Premature Infants (HIFI) (1)
Hispanic Community Health Study / Study of Latinos (HCHS-SOL) (16)
Honolulu Heart Program (HHP) (22)
Hypertension Detection and Follow-Up Program (HDFP) (11)
Idiopathic Pulmonary Fibrosis Network (IPFnet) AntiCoagulant Effectiveness in Idiopathic Pulmonary Fibrosis (ACE IPF) (5)
Idiopathic Pulmonary Fibrosis Network (IPFnet) Prednisone, Azathioprine, and N-Acetylcysteine: A Study That Evaluates Response in Idiopathic Pulmonary Fibrosis (PANTHER IPF) (4)
Idiopathic Pulmonary Fibrosis Network (IPFnet) Sildenafil Trial of Exercise Performance in Idiopathic Pulmonary Fibrosis (STEP IPF) (1)
Interagency Registry for Mechanically Assisted Circulatory Support (Intermacs) (26)
International Study of Comparative Health Effectiveness with Medical and Invasive Approaches (ISCHEMIA) and ISCHEMIA - Chronic Kidney Disease (ISCHEMIA - CKD) (4)
Lipid Research Clinics (LRC) Coronary Primary Prevention Trial (CPPT) (10)
Lipid Research Clinics (LRC) Prevalence Study (PS) (4)
Long-term Oxygen Treatment Trial (LOTT) (2)
Longitudinal Studies of HIV-Associated Lung Infections and Complications (Lung HIV) (3)
Lung Health Study (LHS) (12)
Magnesium in Coronaries (MAGIC) (5)
Multi-Ethnic Study of Atherosclerosis (MESA) (86)
Multicenter Hemophilia Cohort Studies (MHCS) (5)
Multicenter Study of Hydroxyurea (MSH) (13)
Multiple Risk Factor Intervention Trial for the Prevention of Coronary Heart Disease (MRFIT) (28)
N/A (4)
NHLBI Growth and Health Study (NGHS) (40)
NHLBI Umbilical Cord Blood Unit Collection (CBB) (7)
National Emphysema Treatment Trial (NETT) (13)
National Longitudinal Mortality Study (NLMS) (1)
National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions (GenTAC) (6)
Natural History Study of Non-A, Non-B Post-Transfusion Hepatitis (NANB-TAH) (5)
Occluded Artery Trial (OAT) (4)
Optimal Macronutrient Intake Trial to Prevent Heart Disease (OMNI Heart) (9)
Other (generic) (2)
PREMIER: Lifestyle Interventions for Blood Pressure Control (PREMIER) (10)
Patient Registry for Primary Pulmonary Hypertension (PPH Registry) (5)
Pediatric Heart Network Trial of Pulse Steroid Therapy in Kawasaki Disease (PHN-Kawasaki) (1)
Pediatric Pulmonary and Cardiovascular Complications of Vertically Transmitted HIV Infection (P2C2) (1)
Post Coronary Artery Bypass Graft Study (CABG) (13)
Practice Based Opportunities for Weight Reduction Trial at the University of Pennsylvania (POWER-UP) (1)
Prematurity and Respiratory Outcomes Program (PROP) Core Database Protocol (1)
Prevention and Early Treatment of Acute Lung Injury (PETAL) Crystalloid Liberal or Vasopressors Early Resuscitation in Sepsis (CLOVERS) (2)
Prevention and Early Treatment of Acute Lung Injury (PETAL) Network - Outcomes Related to COVID-19 treated with Hydroxychloroquine among In-patients with symptomatic Disease (ORCHID) (1)
Prevention and Early Treatment of Acute Lung Injury (PETAL) Network – Reevaluation of Systemic Early Neuromuscular Blockade (ROSE) (5)
Prevention and Early Treatment of Acute Lung Injury (PETAL) Network – Vitamin D to Improve Outcomes by Leveraging Early Treatment (VIOLET) (1)
Prevention and Treatment of Hypertension Study (PATHS) (1)
Prevention of Events With Angiotensin-Converting Enzyme Inhibitor Therapy (PEACE) (36)
Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) (2)
Psychophysiological Investigation of Myocardial Ischemia (PIMI) (2)
Puerto Rico Heart Health Program (PRHHP) (22)
Pulmonary Complications of HIV Infection Study (PACS) (1)
Recipient Epidemiology and Donor Evaluation Study III (REDS III) Vein to Vein Databases (2)
Registry Evaluation of Vital Information for VADs in Ambulatory Life (REVIVAL) (1)
Resuscitation Outcomes Consortium (ROC) Amiodarone, Lidocaine or Neither for Out-Of-Hospital Cardiac Arrest Due to Ventricular Fibrillation or Ventricular Tachycardia (ALPS) (8)
Resuscitation Outcomes Consortium (ROC) Cardiac Epidemiologic Registry (Cardiac Epistry) Version 1 and 2 (5)
Resuscitation Outcomes Consortium (ROC) Cardiac Epidemiologic Registry (Cardiac Epistry) Version 3 (15)
Resuscitation Outcomes Consortium (ROC) Hypertonic Saline Trial Shock Study (HS) and Traumatic Brain Injury Study (TBI) (5)
Resuscitation Outcomes Consortium (ROC) Pragmatic Trial of Airway Management in Out-of-Hospital Cardiac Arrest (PART) (1)
Resuscitation Outcomes Consortium (ROC) Prehospital Resuscitation Using an Impedance Valve and Early Versus Delayed Analysis (PRIMED) (15)
Resuscitation Outcomes Consortium (ROC) Trial Of Continuous Compressions Versus Standard CPR In Patients With Out-Of-Hospital Cardiac Arrest (CCC) (10)
Retrovirus Epidemiology Donor Study (REDS) Allogeneic Donor and Recipient Repository (RADAR) (18)
Retrovirus Epidemiology Donor Study (REDS) General Leukocyte/Plasma Repository (GLPR) (19)
Retrovirus Epidemiology Donor Study (REDS) HTLV Cohort (HTLV) (28)
Retrovirus Epidemiology Donor Study (REDS) Human Herpes Virus 8 Special Collection from the General Leukocyte/Plasma Repository (HHV8) (16)
Retrovirus Epidemiology Donor Study (REDS): Special Repository Collections (SR) (17)
Retrovirus Epidemiology Donor Study-II (REDS II) Donation and Deferral Database (CORE) (16)
Retrovirus Epidemiology Donor Study-II (REDS II) Donor Iron Status Evaluation Study (RISE) (20)
Retrovirus Epidemiology Donor Study-II (REDS II) Leukocyte Antibodies Prevalence Study (LAPS) (18)
Retrovirus Epidemiology Donor Study-II (REDS II) Molecular Surveillance (MS) (17)
Rule Out Myocardial Ischemia/Infarction by Computer Assisted Tomography (ROMICAT-II) (1)
Sleep Heart Health Study (SHHS) (2)
Studies of Left Ventricular Dysfunction (SOLVD) (26)
Subpopulations and Intermediate Markers in COPD Study (SPIROMICS) (3)
Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT) (10)
Surgical Treatment for Ischemic Heart Failure (STICH) (8)
Systolic Blood Pressure Intervention Trial (SPRINT) (245)
Systolic Blood Pressure Intervention Trial Primary Outcome Paper (SPRINT-POP) Data (192)
Systolic Hypertension in the Elderly Program (SHEP) (19)
The Jackson Heart Study (JHS) (9)
Therapeutic Hypothermia After Pediatric Cardiac Arrest (Out of Hospital) (THAPCA-OH) (1)
Thrombolysis in Myocardial Ischemia Trial II (TIMI II) (6)
Thrombolysis in Myocardial Ischemia Trial III (TIMI III) (3)
Transfusion Safety Study (TSS) (27)
Transfusion-Transmitted Viruses Study (TTVS) (20)
Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist (TOPCAT) (66)
Trial of Activity for Adolescent Girls (TAAG) (2)
Trial to Reduce Alloimmunization to Platelets (TRAP) (5)
Trials of Hypertension Prevention (TOHP) (6)
Viral Activation Transfusion Study (VATS) (29)
Weight Loss Maintenance (WLM) (2)
West Nile Virus Study (WNV) (2)
Women's Angiographic Vitamin and Estrogen Trial (WAVE) (1)
Women's Health Initiative (WHI) (1)
Women's Health Initiative Study (WHI-OS) (42)
Women's Health Initiative: Clinical Trial and Observational Study (WHI-CTOS) (50)
Women's Health Initiative: Clinical Trials (WHI-CT) (28)
Women's Ischemia Syndrome Evaluation (WISE) (1)
NHLBI Division
DBDR (1)
DCVS (5)
DLD (1)
Author
Journal
Annals of internal medicine (1)
Circulation. Cardiovascular quality and outcomes (2)
Health affairs (Project Hope) (1)
Medical decision making : an international journal of the Society for Medical Decision Making (1)
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Studies
Title
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Citation
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Wang EA, Aminawung JA, Wildeman C, Ross JS, Krumholz HM. High incarceration rates among black men enrolled in clinical studies may compromise ability to identify disparities.
Health Aff (Millwood)
2014 May;33(5):848-55.
Toh S, Hernández-Díaz S, Logan R, Rossouw JE, Hernán MA. Coronary heart disease in postmenopausal recipients of estrogen plus progestin therapy: does the increased risk ever disappear? A randomized trial.
Ann Intern Med
2010 Feb 16;152(4):211-7.
Olchanski N, Cohen JT, Neumann PJ, Wong JB, Kent DM. Understanding the Value of Individualized Information: The Impact of Poor Calibration or Discrimination in Outcome Prediction Models.
Med Decis Making
2017 Oct;37(7):790-801. Epub 2017 Apr 11.
Gulati G, Upshaw J, Wessler BS, Brazil RJ, Nelson J, van Klaveren D, Lundquist CM, Park JG, McGinnes H, Steyerberg EW, Van Calster B, Kent DM. Generalizability of Cardiovascular Disease Clinical Prediction Models: 158 Independent External Validations of 104 Unique Models.
Circ Cardiovasc Qual Outcomes
2022 Apr;15(4):e008487. Epub 2022 Mar 31.
Burke JF, Hayward RA, Nelson JP, Kent DM. Using internally developed risk models to assess heterogeneity in treatment effects in clinical trials.
Circ Cardiovasc Qual Outcomes
2014 Jan;7(1):163-9. Epub 2014 Jan 14.
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