Pubmed ID: 42085260

Journal: American journal of respiratory and critical care medicine

Publication Date: March 21, 2026

Authors: Siempos II, Kotanidou A, Papoutsi E, Gkirgkiris K, Dimopoulou I

Cite As: Papoutsi E, Gkirgkiris K, Dimopoulou I, Kotanidou A, Siempos II. Relative contribution of driving pressure and respiratory rate to mortality in ARDS depends on age. Am J Respir Crit Care Med 2026 Mar 21. Epub 2026 Mar 21.

Studies:

• Acute Respiratory Distress Network (ARDSNet) Studies 01 and 03 Lower versus higher tidal volume, ketoconazole treatment and lisofylline treatment (ARMA/KARMA/LARMA)
• Acute Respiratory Distress Network (ARDSNet) Studies 06 and 08 Prospective, Randomized, Multicenter Trial of Aerosolized Albuterol Versus Placebo for the Treatment of Acute Lung Injury (ALTA)
• Acute Respiratory Distress Network (ARDSNet) Studies 07, 08, 09, 11, and 12 Early Versus Delayed Enteral Feeding to Treat People with Acute Lung Injury or Acute Respiratory Distress Syndrome (EDEN)
• Acute Respiratory Distress Network (ARDSNet) Studies 10 and 12 Statins for Acutely Injured Lungs from Sepsis (SAILS)
• Acute Respiratory Distress Network (ARDSNet) Study 04 Assessment of Low tidal Volume and elevated End-expiratory volume to Obviate Lung Injury (ALVEOLI)
• Acute Respiratory Distress Network (ARDSNet) Study 05 Fluid and Catheter Treatment Trial (FACTT)
• Prevention and Early Treatment of Acute Lung Injury (PETAL) Network – Reevaluation of Systemic Early Neuromuscular Blockade (ROSE)